SCHEMBL10061342

SCHEMBL10061342

N#Cc1ccc(C=Cc2c3ccccc3c(C=Cc3ccc(C#N)cc3)c3ccccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAPT P10636 4/20 0.49
LMNA P02545 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KDM4E B2RXH2 4/20 0.48
NPC1 O15118 1/20 0.48
GLA P06280 1/20 0.48
POLB P06746 1/20 0.48
FBP1 P09467 1/20 0.46
NR1H3 Q13133 1/20 0.45
TSHR P16473 1/20 0.44
SNCA P37840 1/20 0.43
PTGES2 Q9H7Z7 1/20 0.42
HDAC2 Q92769 2/20 0.41
HTT P42858 1/20 0.41
P4HB P07237 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
KMT2A Q03164 2/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13928930 1.00 ALDH1A1 (0.49) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL10062089 0.96 ALDH1A1 (0.50) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL12946529 0.94 ALDH1A1 (0.45) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL1630806 0.88 ALDH1A1 (0.41) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL1687900 0.88 FBP1 (0.48) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL1687856 0.88 CA1 (0.47) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL10450860 0.85 FBP1 (0.53) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL700237 0.83 ALDH1A1 (0.59) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL700236 0.83 ALDH1A1 (0.59) ALDH1A1MAPTLMNAL3MBTL1KDM4E
SCHEMBL11486259 0.83 ALDH1A1 (0.59) ALDH1A1MAPTLMNAL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed