SCHEMBL1687900

SCHEMBL1687900

N#Cc1ccc(C=Cc2c3ccccc3c(C=Cc3cccc(C#N)c3)c3ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.48
P4HB P07237 9/20 0.43
RAF1 P04049 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.41
POLB P06746 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GRIN2D O15399 2/20 0.40
GRIN3B O60391 2/20 0.40
GRIN1 Q05586 2/20 0.40
GRIN2A Q12879 2/20 0.40
GRIN2B Q13224 2/20 0.40
GRIN2C Q14957 2/20 0.40
GRIN3A Q8TCU5 2/20 0.40
TSHR P16473 1/20 0.39
NR1H3 Q13133 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10062089 0.89 ALDH1A1 (0.50) FBP1ALDH1A1MAPTKDM4ENPC1
SCHEMBL13928930 0.88 ALDH1A1 (0.49) FBP1P4HBRAF1ALDH1A1MAPT
SCHEMBL10061342 0.88 ALDH1A1 (0.49) FBP1P4HBRAF1ALDH1A1MAPT
SCHEMBL9190221 0.88 FBP1 (0.57) FBP1P4HBALDH1A1MAPTLMNA
SCHEMBL21574806 0.88 FBP1 (0.57) FBP1P4HBALDH1A1MAPTLMNA
SCHEMBL1687873 0.88 FBP1 (0.57) FBP1P4HBALDH1A1MAPTLMNA
SCHEMBL1687907 0.88 FBP1 (0.57) FBP1P4HBALDH1A1MAPTLMNA
SCHEMBL1629352 0.87 FBP1 (0.43) FBP1P4HBRAF1GRIN2DGRIN3B
SCHEMBL21574844 0.85 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL9186668 0.85 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed