SCHEMBL10061549

SCHEMBL10061549

N#Cc1cccc(C=Cc2ccc3ccccc3c2)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.61
FBP1 P09467 1/20 0.51
PTGS1 P23219 1/20 0.50
P4HB P07237 6/20 0.48
NQO2 P16083 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GRIN2D O15399 2/20 0.43
GRIN3B O60391 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
GRIN3A Q8TCU5 2/20 0.43
HRH4 Q9H3N8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11491866 0.86 RELA (0.66) RELAFBP1PTGS1NQO2ALDH1A1
SCHEMBL9186663 0.85 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL21574844 0.85 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL9186668 0.85 FBP1 (0.61) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL2774364 0.85 FBP1 (0.65) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL1687910 0.85 FBP1 (0.65) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL7338887 0.84 RELA (0.63) RELAFBP1PTGS1NQO2ALDH1A1
SCHEMBL7338903 0.84 RELA (0.63) RELAFBP1PTGS1NQO2ALDH1A1
SCHEMBL1405480 0.83 FBP1 (0.59) FBP1P4HBGRIN2DGRIN3BGRIN1
SCHEMBL10661672 0.83 FBP1 (0.59) FBP1P4HBGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed