Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 2/20 | 0.63 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338903 | 1.00 | RELA (0.63) | RELAPLGPLAUPLATKLK1 | |
| SCHEMBL11491866 | 0.87 | RELA (0.66) | RELAPLGPLAUPLATKLK1 | |
| SCHEMBL10068047 | 0.87 | RELA (0.52) | RELAPLGPLAUPLATKLK1 | |
| SCHEMBL10061549 | 0.84 | RELA (0.61) | RELAALDH1A1MAPTGLASMN1; SMN2 | |
| SCHEMBL9803853 | 0.82 | ALDH1A1 (0.59) | RELAALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL700237 | 0.82 | ALDH1A1 (0.59) | RELAALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL11486259 | 0.82 | ALDH1A1 (0.59) | RELAALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL700236 | 0.82 | ALDH1A1 (0.59) | RELAALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL11209385 | 0.82 | RELA (0.91) | RELAPLGPLAUPLATKLK1 | |
| SCHEMBL11268864 | 0.82 | RELA (0.91) | RELAPLGPLAUPLATKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284796-B1 | NAPHTHAMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-09-04 | — | — | US | disclosed |
| US-6258822-B1 | ENZYME INHIBITORS OF NAPHTHALENE AMIDINE COMPOUNDS | ABBOTT LABORATORIES | 2001-07-10 | — | — | US | disclosed |