Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9068628 | 0.89 | ALDH1A1 (0.52) | HPGDALDH1A1LMNAMAPK1RAB9A | |
| SCHEMBL28895521 | 0.81 | CES2 (0.50) | HPGDALDH1A1LMNAMAPK1CES2 | |
| SCHEMBL11408016 | 0.79 | ALDH1A1 (0.51) | HPGDALDH1A1LMNAMAPK1RAB9A | |
| SCHEMBL12433229 | 0.78 | NPC1 (0.54) | CES2CES1RAB9ANPC1MEN1 | |
| SCHEMBL1175407 | 0.78 | NPC1 (0.54) | CES2CES1RAB9ANPC1MEN1 | |
| SCHEMBL14415748 | 0.77 | HPGD (0.48) | HPGDALDH1A1LMNAMAPK1CES2 | |
| SCHEMBL12510836 | 0.76 | ALDH1A1 (0.45) | HPGDALDH1A1LMNAMAPK1CES2 | |
| SCHEMBL1176115 | 0.76 | NPC1 (0.52) | HPGDALDH1A1MAPK1CES2CES1 | |
| SCHEMBL7638576 | 0.76 | CES2 (0.61) | HPGDALDH1A1MAPK1CES2CES1 | |
| SCHEMBL5533631 | 0.75 | ALDH1A1 (0.50) | HPGDALDH1A1LMNAMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158678-B2 | Photoabsorbing, highly conjugated compounds of cyanoacrylic esters, sunscreen compositions and methods of use | CPH INNOVATIONS CORP. | 2012-04-17 | — | — | US | disclosed |
| US-8158678-B2 | Photoabsorbing, highly conjugated compounds of cyanoacrylic esters, sunscreen compositions and methods of use | CPH INNOVATIONS CORP. | 2012-04-17 | — | — | US | disclosed |