Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL2204930 | 0.94 | TSHR (0.59) | DRD3DRD2PARP1TSHRCYP19A1 | |
| SCHEMBL1556706 | 0.87 | DRD3 (0.51) | DRD3DRD2PARP1TSHRCYP19A1 | |
| SCHEMBL1555687 | 0.85 | DRD3 (0.58) | DRD3DRD2PARP1TSHRCYP19A1 | |
| SCHEMBL46283 | 0.84 | TSHR (0.67) | DRD3DRD2PARP1TSHRALDH1A1 | |
| SCHEMBL21974861 | 0.84 | TSHR (0.67) | DRD3DRD2PARP1TSHRALDH1A1 | |
| SCHEMBL18706863 | 0.79 | DRD3 (0.59) | DRD3DRD2CYP19A1ALDH1A1DRD1 | |
| Phenol SCHEMBL28650467 | 0.77 | PARP1 (0.62) | DRD3DRD2PARP1TSHRCA12 | |
| SCHEMBL22325842 | 0.77 | DRD2 (0.46) | DRD3DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL31125349 | 0.77 | DRD3 (0.53) | DRD3DRD2CYP19A1HTR2AHTR2C | |
| SCHEMBL1135239 | 0.77 | DRD3 (0.53) | DRD3DRD2CYP19A1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8137700-B2 | Main chain acid-degradable polymers for the delivery of bioactive materials | U.S. DEPARTMENT OF ENERGY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | CTSA, GAA, CTSB | DRD3 4809/4885DRD2 4799/4885PARP1 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.