Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10028144 | 0.90 | MEN1 (0.32) | SMN1; SMN2THRB | |
| SCHEMBL10028147 | 0.79 | KDM4E (0.33) | LMNASMN1; SMN2HTTMAPTRAB9A | |
| SCHEMBL10028142 | 0.77 | KDM4E (0.33) | LMNAMAPTTHRB | |
| SCHEMBL10028207 | 0.73 | KDM4E (0.31) | MAPT | |
| SCHEMBL13747948 | 0.71 | RAB9A (0.41) | LMNAMAPTRAB9A | |
| SCHEMBL12648876 | 0.71 | TSHR (0.39) | LMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL13948918 | 0.71 | TSHR (0.39) | LMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL13948915 | 0.68 | TSHR (0.54) | LMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL12374376 | 0.68 | TSHR (0.54) | LMNASMN1; SMN2MAPTRAB9A | |
| SCHEMBL18560262 | 0.68 | TSHR (0.54) | LMNASMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114531-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100013381-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | L1CAM, SOD1, SLC40A1 | LMNA 2101/4885SMN1; SMN2 3914/4885HTT 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.