SCHEMBL10062639

SCHEMBL10062639

O=S(=O)(Oc1cccc(OS(=O)(=O)C(F)(F)F)c1-c1cccc2c1sc1ccccc12)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 4/20 0.40
▸ PARP14 Q460N5 1/20 0.40
▸ ALOX5 P09917 1/20 0.39
▸ PRKDC P78527 5/20 0.36
▸ PIK3CD O00329 2/20 0.33
▸ PIK3CB P42338 2/20 0.33
▸ BRD4 O60885 1/20 0.33
▸ PIK3CA P42336 1/20 0.33
▸ MTOR P42345 1/20 0.33
▸ PIK3CG P48736 1/20 0.33
▸ KCNH2 Q12809 1/20 0.33
▸ BRDT Q58F21 1/20 0.33
▸ HTR1D P28221 1/20 0.33
▸ DRD3 P35462 1/20 0.33
▸ MAPK3 P27361 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ MAP2K1 Q02750 1/20 0.33
▸ GPR3 P46089 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ TNKS O95271 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10029308 0.92 PRKDC (0.39) DRD2PARP14ALOX5PRKDCHTR1D
SCHEMBL3718035 0.88 ALOX5 (0.38) DRD2PARP14ALOX5HTR1DDRD3
SCHEMBL17030508 0.82 ALOX5 (0.48) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16543279 0.81 ALOX5 (0.47) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL7795700 0.78 DRD2 (0.44) DRD2ALDH1A1MAPTTDP1CA2
SCHEMBL18820392 0.77 MAPT (0.38) DRD2HTR1DDRD3GPR3POLB
SCHEMBL16596209 0.76 ALOX5 (0.43) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL16543291 0.76 ALOX5 (0.43) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL18820581 0.76 CDC14B (0.38) DRD2PARP14PRKDCMAPK3MAPK1
SCHEMBL28568213 0.75 DRD2 (0.46) DRD2MAPK1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160372685-A1 Dibenzothiophene-Containing Materials in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2016-12-22 — — US disclosed
US-9123903-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-01 — — US disclosed
US-20140008643-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2014-01-09 — — US disclosed
US-8580402-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 — — US disclosed
US-20120012829-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2012-01-19 — — US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 — — US disclosed
US-8007927-B2 Dibenzothiophene-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2011-08-30 — — US disclosed
WO-2009085344-A2 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 — — WO disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 — — US disclosed
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090167162-A1 DIBENZOTHIOPHENE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES DDT, BPNT1, DBF4 DRD2 107/4885PARP14 2217/4885ALOX5 1131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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