SCHEMBL10064128

SCHEMBL10064128

CCC(C)c1ccc2c(c1)C(=O)OC2

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 15/20 0.44
MAOB P27338 14/20 0.44
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10064135 0.88 MAPT (0.50) MAOAMAOBHDAC4HDAC2HDAC8
SCHEMBL18704854 0.86 MAOA (0.46) MAOAMAOBCYP3A4
SCHEMBL14726021 0.83 MAOA (0.50) MAOAMAOBALDH1A1GAACYP3A4
SCHEMBL7879420 0.78 MAOA (0.42) MAOAMAOBCYP3A4
SCHEMBL26057140 0.76 HDAC4 (0.41) MAOAMAOBHDAC4HDAC2HDAC8
SCHEMBL6056909 0.76 HDAC4 (0.42) MAOAMAOBHDAC4HDAC2HDAC8
SCHEMBL4889560 0.74 ALDH1A1 (0.46) HDAC4HDAC2HDAC8ALDH1A1GAA
SCHEMBL19770243 0.74 MAPT (0.49) MAOAMAOBALDH1A1GAACYP3A4
SCHEMBL5094360 0.74 MAPT (0.46) MAOAMAOBALDH1A1GAACYP3A4
SCHEMBL14177758 0.74 HDAC4 (0.39) HDAC4HDAC2HDAC8ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623590-B2 Pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-01-07 US disclosed
US-20120108043-A1 PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
US-7374860-B2 Positive resist composition and pattern forming method using the same FUJI FILM CORPORATION (JP) 2008-05-20 US disclosed