SCHEMBL10064563

SCHEMBL10064563

CCN(CC(=O)O)C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.41
PGR P06401 1/20 0.41
ADRA2B P18089 1/20 0.41
HTR2A P28223 1/20 0.41
HRH1 P35367 1/20 0.41
KCNH2 Q12809 1/20 0.41
FFAR3 O14843 1/20 0.39
TDP1 Q9NUW8 2/20 0.33
EYA2 O00167 1/20 0.33
APP P05067 1/20 0.33
ACE P12821 1/20 0.33
CYP1A2 P05177 1/20 0.33
FDPS P14324 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CHRM2 P08172 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
DRD1 P21728 1/20 0.32
SLC6A2 P23975 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17636225 1.00 ADRA2A (0.41) ADRA2APGRADRA2BHTR2AHRH1
SCHEMBL345564 0.88 FFAR3 (0.38) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL22120 0.88 FFAR3 (0.38) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL6320153 0.88 FFAR3 (0.38) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL18762319 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL15548723 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL18762316 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL5688211 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL31094049 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP
SCHEMBL31516444 0.86 FFAR3 (0.36) ADRA2AFFAR3TDP1EYA2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449868-B2 Preparation of cationic nanoparticles and personal care compositions comprising said nanoparticles BASF SE (DE) 2013-05-28 US disclosed
US-8258248-B2 Preparation of cationic terpolymers and personal care compositions comprising said terpolymers BASF SE (DE) 2012-09-04 US disclosed
US-8216596-B2 4-Hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine, citric acid and a body care product; hindered amine salt compounds provide outstanding protection against light-induced fading BASF SE (DE) 2012-07-10 US disclosed
US-8148318-B2 Home or fabric care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US disclosed
US-8147814-B2 Personal care compositions comprising certain dye-polymer complexes BASF SE (DE) 2012-04-03 US disclosed
US-7700078-B2 Stabilization of body-care and household products CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-04-20 US disclosed
US-7678381-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-03-16 US disclosed
US-7632795-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-12-15 US disclosed
US-7618644-B2 Sterically hindered amine salts having an N-(alkoxy, cycloalkoxy or aralkoxy)2,2,6,6-tetraalkylsubstituted piperidine moiety; discoloration inhibition, colorfastness CIBA SPECIALTY CHEMICALS CORP. (US) 2009-11-17 US disclosed
US-7618618-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. (US) 2009-11-17 US disclosed
US-20090060849-A1 Personal care compositions comprising certain dye-polymer complexes BASF SE (DE) 2009-03-05 US disclosed
US-20080255251-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-10-16 US disclosed
US-20080253981-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-10-16 US disclosed
US-20080250572-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-10-16 US disclosed
US-7429545-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-09-30 US disclosed
US-7410936-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-08-12 US disclosed
US-20080009550-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2008-01-10 US disclosed
US-20070294837-A1 Stabilized body care products, household products, textiles and fabrics LUPIA JOSEPH A 2007-12-27 US disclosed
US-7309682-B2 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-12-18 US disclosed
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CUTA, NISCH, DSC1 ADRA2A 3832/4885PGR 4869/4885ADRA2B 4380/4885
US-20080253981-A1 Stabilized body care products, household products, textiles and fabrics DSC1, CUTA, DSG1 ADRA2A 4716/4885PGR 4879/4885ADRA2B 4804/4885
US-20090060849-A1 Personal care compositions comprising certain dye-polymer complexes ERCC5, XRCC5, ERCC1 ADRA2A 4734/4885PGR 1716/4885ADRA2B 4696/4885
US-20080255251-A1 Stabilized body care products, household products, textiles and fabrics DSC1, CUTA, DSG1 ADRA2A 4716/4885PGR 4879/4885ADRA2B 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.