Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 6/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18532484 | 0.84 | ATM (0.42) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL786222 | 0.83 | ATM (0.46) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL12221446 | 0.81 | GRM1 (0.41) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL6854496 | 0.81 | CYP19A1 (0.47) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL10045202 | 0.79 | ATM (0.51) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL6854606 | 0.79 | ATM (0.51) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL13657228 | 0.76 | GRM1 (0.39) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL29066362 | 0.76 | CTSV (0.44) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL18467155 | 0.76 | CYP19A1 (0.41) | ATMGRM1CYP19A1CTSVCTSL | |
| SCHEMBL14950789 | 0.74 | ATM (0.41) | ATMGRM1CYP19A1CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097396-B2 | Reduced defects; improved shape and stability of latent image; comprised of acrylate copolymer having lactone ring and polycyclic ring containing monomers; increased alkali solubility under action of acid generator upon exposure | TOKYO OHKA KOGYO CO., LTD. (JP) | 2012-01-17 | — | — | US | disclosed |