Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065051 | 0.86 | PSEN1 (0.40) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL11901256 | 0.79 | NOD2 (0.56) | NOD2NOD1MEN1KMT2AAR | |
| SCHEMBL12229940 | 0.78 | NOD2 (0.49) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL12392496 | 0.76 | NOD2 (0.48) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL13765387 | 0.74 | NOD2 (0.46) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL8874979 | 0.72 | NOD2 (0.49) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL2732415 | 0.72 | MEN1 (0.45) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL7467719 | 0.71 | NOD2 (0.57) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL13765375 | 0.71 | MEN1 (0.45) | NOD2NOD1MEN1KMT2AALDH1A1 | |
| SCHEMBL2005697 | 0.69 | NOD2 (0.53) | NOD2NOD1ALDH1A1ALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059568-A1 | NOVEL WATER-SOLUBLE INDOLOBENZAZEPINE MOLECULES DEMONSTRATING ANTIMITOTIC, ANTIVASCULAR, AND ANTITUMOR ACTIVITIES IN VIVO | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2012-05-10 | — | — | WO | disclosed |