Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874498 | 0.86 | ACKR3 (0.43) | ACKR3LMNAHTR3ASMYD3 | |
| SCHEMBL874709 | 0.82 | CA12 (0.43) | ALDH1A1MAPT | |
| SCHEMBL882752 | 0.71 | NAMPT (0.46) | — | |
| SCHEMBL4294367 | 0.65 | ALDH1A1 (0.52) | LMNAHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL717648 | 0.64 | L3MBTL1 (0.58) | ALDH1A1MAPT | |
| SCHEMBL875174 | 0.63 | NPC1 (0.40) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL15614408 | 0.62 | NPC1 (0.55) | LMNARAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL104343 | 0.59 | HRH3 (0.52) | RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL4296566 | 0.59 | NPSR1 (0.61) | RAB9ANPC1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL12065982 | 0.59 | L3MBTL1 (0.55) | LMNARAB9ANPC1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |