Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426824 | 0.94 | TOP2A (0.38) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL10065367 | 0.92 | TOP2A (0.43) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL10065225 | 0.91 | TOP2A (0.41) | TOP2AKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL10065107 | 0.90 | TOP2A (0.41) | TOP2AKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL10065349 | 0.90 | TOP2A (0.38) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL13426373 | 0.87 | TOP2A (0.39) | TOP2AKDM4EATML3MBTL1ALDH1A1 | |
| SCHEMBL13426778 | 0.86 | TOP2A (0.42) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL27049528 | 0.86 | TOP2A (0.39) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL10065398 | 0.85 | KDM4E (0.39) | TOP2AKDM4EATMSIRT2SIRT1 | |
| SCHEMBL10065400 | 0.85 | KDM4E (0.39) | TOP2AKDM4EATMSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735597-B2 | Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using benzoxazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| US-8735597-B2 | Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using benzoxazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20120104376-A1 | Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Benzoxazole Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-05-03 | — | — | US | disclosed |
| US-20120104376-A1 | Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Benzoxazole Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-05-03 | — | — | US | disclosed |
| US-8093399-B2 | Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using benzoxazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-8093399-B2 | Benzoxazole derivative, and light-emitting element, light-emitting device, and electronic device using benzoxazole derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20100060154-A1 | Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Benzoxazole Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-03-11 | — | — | US | disclosed |
| US-20100060154-A1 | Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Benzoxazole Derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100060154-A1 | Benzoxazole Derivative, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using Benzoxazole Derivative | GABRA1, GABRA4, GABRA5 | TOP2A 1535/4885KDM4E 3212/4885ATM 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.