Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSH | P09668 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.53 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.52 |
| ▸ | CALCR | P30988 | 5/20 | 0.52 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | MC1R | Q01726 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984377 | 0.96 | CTSL (0.55) | CTSLCTSSCTSKCTSHOPRM1 | |
| SCHEMBL31014198 | 0.90 | MAPK8 (0.56) | CTSLCTSSCTSKCTSHCALCR | |
| SCHEMBL14096140 | 0.89 | RAMP3 (0.60) | CTSLCTSSCTSKCTSHRAMP3 | |
| SCHEMBL30248733 | 0.89 | MAPK8 (0.58) | CALCRMAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL13028975 | 0.89 | RAMP3 (0.65) | CTSLCTSSCTSKCTSHRAMP3 | |
| SCHEMBL31014203 | 0.88 | MAPK8 (0.60) | CTSLCTSSCTSKCTSHCALCR | |
| SCHEMBL25027403 | 0.87 | MAPK8 (0.53) | CALCRIL23RMAPK8MAPK9MAPK10 | |
| SCHEMBL30248429 | 0.87 | MAPK8 (0.62) | CALCRIL23RMAPK8MAPK9MAPK10 | |
| SCHEMBL25028492 | 0.86 | MAPK8 (0.53) | CTSLCTSSCTSKCTSHCALCR | |
| SCHEMBL25028399 | 0.85 | MAPK8 (0.53) | CTSLCTSSCTSKCTSHCALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | BRACCO IMAGING S.P.A. (IT) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | TAGLN2, TTN, TXLNA | CTSL 2142/4885CTSS 3165/4885CTSK 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.