SCHEMBL13028975

SCHEMBL13028975

CSCC[C@H](NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ RAMP3 O60896 10/20 0.65
▸ CALCR P30988 10/20 0.65
▸ MC4R P32245 2/20 0.62
▸ MC5R P33032 2/20 0.62
▸ MC3R P41968 2/20 0.62
▸ MC1R Q01726 2/20 0.62
▸ TFPI P10646 4/20 0.61
▸ CTSL P07711 2/20 0.56
▸ CTSS P25774 2/20 0.56
▸ CTSK P43235 2/20 0.56
▸ CTSH P09668 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14096140 0.94 RAMP3 (0.60) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL10065713 0.89 RAMP3 (0.61) RAMP3CALCRTFPI
SCHEMBL12984377 0.89 CTSL (0.55) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL10065575 0.89 CTSL (0.55) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL12984102 0.85 RAMP3 (0.66) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL13028816 0.83 TFPI (0.62) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL31014198 0.83 MAPK8 (0.56) CALCRTFPICTSLCTSSCTSK
SCHEMBL13027243 0.82 RAMP3 (0.62) RAMP3CALCRMC4RMC5RMC3R
SCHEMBL25027403 0.81 MAPK8 (0.53) CALCRTFPI
Gfttgrrgdlatihgmnrpf SCHEMBL29847206 0.81 NPY2R (0.66) RAMP3CALCRTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100316563-A1 Method For The Preparation Of New Oligoclonal Antibodies BRACCO IMAGING S.P.A. (IT) 2010-12-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316563-A1 Method For The Preparation Of New Oligoclonal Antibodies APOB, APOL1, FCGR3B RAMP3 3589/4885CALCR 1054/4885MC4R 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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