Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260077 | 0.97 | THRB (0.59) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL19757195 | 0.95 | THRB (0.55) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL26126205 | 0.95 | TSHR (0.59) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL13572565 | 0.95 | TSHR (0.59) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL12356583 | 0.95 | TSHR (0.59) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL12173361 | 0.95 | TSHR (0.59) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL39887 | 0.92 | THRB (0.71) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL20414484 | 0.92 | TSHR (0.51) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL14195437 | 0.92 | TSHR (0.51) | THRBTSHRHPGDHTTALDH1A1 | |
| SCHEMBL14588426 | 0.91 | TSHR (0.54) | THRBTSHRHPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) | 2017-12-28 | — | — | US | disclosed |
| EP-3088426-A1 | COMPOUND CONTAINING MESOGENIC GROUP, AND MIXTURE, COMPOSITION, AND OPTICALLY ANISOTROPIC BODY USING SAID COMPOUND | DIC Corporation (JP) | 2016-11-02 | — | — | EP | disclosed |
| US-8252389-B2 | Mesogenic dimers | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-08-28 | — | — | US | disclosed |
| US-8252389-B2 | Mesogenic dimers | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-08-28 | — | — | US | disclosed |
| US-20120026236-A1 | INKJET RECORDING METHOD, AND PRINTED MATERIAL | FUJIFILM CORPORATION (JP) | 2012-02-02 | — | — | US | disclosed |
| US-20100222534-A1 | Mesogenic Dimers | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-02 | — | — | US | disclosed |
| US-20100222534-A1 | Mesogenic Dimers | MERCK PATENT GESELLSCHAFT (DE) | 2010-09-02 | — | — | US | disclosed |
| WO-2007131336-A1 | NEW MATERIALS FOR LITHOGRAPHIC PLATES COATINGS, LITHOGRAPHIC PLATES AND COATINGS CONTAINING SAME, METHODS OF PREPARATION AND USE | AMERICAN DYE SOURCE INC. (CA) | 2007-11-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222534-A1 | Mesogenic Dimers | PML, MLEC, MTX2 | THRB 4780/4885TSHR 4773/4885HPGD 3778/4885 |
| US-20170369783-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC OBJECT | VIM, SMCHD1, SMC4 | THRB 4851/4885TSHR 4634/4885HPGD 4211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.