Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27534818 | 0.78 | KMT2A (0.52) | HTTL3MBTL1POLBNPSR1MTNR1B | |
| SCHEMBL11263712 | 0.78 | KMT2A (0.49) | HTTL3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL15243098 | 0.78 | L3MBTL1 (0.48) | HTTL3MBTL1POLBNPSR1MTNR1B | |
| SCHEMBL8473051 | 0.77 | PTGS2 (0.64) | HTTL3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL15695551 | 0.77 | PTGS1 (0.51) | HTTL3MBTL1POLBNPSR1MTNR1B | |
| SCHEMBL362211 | 0.77 | PTGS2 (0.64) | HTTL3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL7885098 | 0.77 | PTGS2 (0.64) | HTTL3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL28968065 | 0.76 | TSHR (0.49) | HTTL3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL4554195 | 0.75 | KMT2A (0.53) | HTTL3MBTL1POLBNPSR1MTNR1B | |
| SCHEMBL9729192 | 0.75 | KMT2A (0.53) | HTTL3MBTL1POLBNPSR1MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | disclosed |