Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12984158 | 0.92 | CAPN1 (0.56) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL10065714 | 0.86 | PRSS1 (0.50) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL12985194 | 0.81 | FOLH1 (0.63) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL8106640 | 0.81 | FOLH1 (0.54) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL8115912 | 0.81 | FOLH1 (0.61) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL23879992 | 0.80 | F2 (0.67) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL19229658 | 0.80 | PKM (0.70) | PKMFOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL10066225 | 0.80 | FOLH1 (0.61) | CAPN1PKMFOLH1PRSS1PRSS2 | |
| SCHEMBL17171624 | 0.79 | PKM (0.68) | PKMFOLH1PRSS1PRSS2PRSS3 | |
| SCHEMBL17126770 | 0.78 | F2 (0.67) | CAPN1PKMFOLH1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | BRACCO IMAGING S.P.A. (IT) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | TAGLN2, TTN, TXLNA | CAPN1 2006/4885PKM 2923/4885FOLH1 3275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.