Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.43 |
| ▸ | ELOC | Q15369 | 1/20 | 0.43 |
| ▸ | ELOB | Q15370 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.40 |
| ▸ | CALCR | P30988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066226 | 0.86 | CAPN1 (0.58) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10066201 | 0.83 | PRSS1 (0.49) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12984158 | 0.81 | CAPN1 (0.56) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10065813 | 0.80 | PRSS1 (0.47) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12984633 | 0.79 | APLNR (0.49) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10066224 | 0.77 | RAMP3 (0.51) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19229658 | 0.74 | PKM (0.70) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL10215078 | 0.73 | PKM (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL12985194 | 0.72 | FOLH1 (0.63) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL17171624 | 0.72 | PKM (0.68) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | BRACCO IMAGING S.P.A. (IT) | 2012-06-28 | — | — | US | disclosed |
| US-20100316563-A1 | Method For The Preparation Of New Oligoclonal Antibodies | BRACCO IMAGING S.P.A. (IT) | 2010-12-16 | — | — | US | disclosed |
| US-20100316563-A1 | Method For The Preparation Of New Oligoclonal Antibodies | BRACCO IMAGING S.P.A. (IT) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316563-A1 | Method For The Preparation Of New Oligoclonal Antibodies | APOB, APOL1, FCGR3B | PRSS1 3190/4885PRSS2 2304/4885PRSS3 2581/4885 |
| US-20120165211-A1 | Human Antibodies Cross-Reacting With A Bacterial And A Self Antigen From Atherosclerotic Plaques | TAGLN2, TTN, TXLNA | PRSS1 2410/4885PRSS2 2765/4885PRSS3 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.