Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16192920 | 0.87 | NOX1 (0.56) | ALDH1A1CYP3A4MAPTGAAKDM4E | |
| SCHEMBL27654972 | 0.87 | NOX1 (0.56) | ALDH1A1TAS2R38HSD17B10CYP3A4MAPT | |
| SCHEMBL27633944 | 0.87 | CYP1A2 (0.69) | ALDH1A1CYP3A4MAPTGAAKDM4E | |
| SCHEMBL27633763 | 0.87 | MAPT (0.73) | ALDH1A1TAS2R38HSD17B10CYP3A4MAPT | |
| SCHEMBL17637643 | 0.87 | MAPT (0.73) | ALDH1A1CYP3A4MAPTGAAKDM4E | |
| SCHEMBL16193007 | 0.82 | GAA (0.46) | ALDH1A1MAPTGAAKDM4ETHRB | |
| SCHEMBL17637667 | 0.82 | RAB9A (0.59) | ALDH1A1MAPTGAAKDM4ETHRB | |
| SCHEMBL3985920 | 0.82 | POLB (0.59) | ALDH1A1MAPTKMT2ARAB9AMEN1 | |
| SCHEMBL28410091 | 0.82 | RAB9A (0.68) | ALDH1A1CYP3A4MAPTGAAKDM4E | |
| SCHEMBL9813379 | 0.81 | MAPT (0.49) | ALDH1A1TAS2R38HSD17B10CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320562-B | Method for producing isothiocyanate | 旭化成株式会社 | 2022-08-16 | — | — | CN | disclosed |
| CN-113880741-A | Method for producing isothiocyanate | 旭化成株式会社 | 2022-01-04 | — | — | CN | disclosed |
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| EP-3363785-B1 | ISOTHIOCYANATE PRODUCTION METHODS | ASAHI CHEMICAL IND (JP) | 2020-09-16 | — | — | EP | disclosed |
| CN-111320562-A | Method for producing isothiocyanate | 旭化成株式会社 | 2020-06-23 | — | — | CN | disclosed |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-08-01 | — | — | US | disclosed |
| EP-3214071-B1 | ISOTHIOCYANATE COMPOSITION | ASAHI CHEMICAL IND (JP) | 2019-07-03 | — | — | EP | disclosed |
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2019-06-04 | — | — | US | disclosed |
| EP-3363785-A1 | ISOTHIOCYANATE PRODUCTION METHODS | Asahi Kasei Chemicals Corporation (JP) | 2018-08-22 | — | — | EP | disclosed |
| EP-3214071-A1 | ISOTHIOCYANATE COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2017-09-06 | — | — | EP | disclosed |
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-2966060-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2016-01-13 | — | — | EP | disclosed |
| WO-2011011065-A1 | METHOD AND SYSTEM FOR EFFECTING CHANGES IN PIGMENTED TISSUE | MOAZED KAMBIZ THOMAS (US) | 2011-01-27 | — | — | WO | disclosed |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | FUJIFILM CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| EP-2202220-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
| CN-1824651-A | Method of synthesizing thio methyl carbamater from aniline under normal pressure | DALIAN CHEMICAL PHYSICS INST (CN) | 2006-08-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11046645-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | ALDH1A1 723/4885TAS2R38 320/4885HSD17B10 915/4885 |
| US-20160016901-A1 | ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION | TST, SLCO4C1, SLCO2B1 | ALDH1A1 723/4885TAS2R38 320/4885HSD17B10 915/4885 |
| US-20190233371-A1 | Isothiocyanate Production Method, Composition for Transporting and Storing N-Substituted O-Substituted Thiocarbamate, and Isothiocyanate Composition | TST, SLCO4C1, SLCO2B1 | ALDH1A1 723/4885TAS2R38 320/4885HSD17B10 915/4885 |
| US-20100286353-A1 | ACETYLENE COMPOUND, SALT THEREOF, CONDENSATE THEREOF, AND COMPOSITION THEREOF | KAT8, HDAC10, SSRP1 | ALDH1A1 1480/4885TAS2R38 4144/4885HSD17B10 272/4885 |
| US-10308601-B2 | Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition | TST, SLCO4C1, SLCO2B1 | ALDH1A1 723/4885TAS2R38 320/4885HSD17B10 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.