SCHEMBL10067477

SCHEMBL10067477

c1ccc2c(c1)c1ccccc1n2CN1CCCCC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2C19 P33261 1/20 0.61
POLB P06746 2/20 0.60
RAD52 P43351 2/20 0.53
KDM4E B2RXH2 4/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53
ALOX12 P18054 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GLA P06280 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 1/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CNR2 P34972 2/20 0.47
HTR7 P34969 3/20 0.46
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
ADRA2A P08913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22023408 0.98 CYP1A2 (0.64) CYP1A2CYP2C19POLBRAD52KDM4E
SCHEMBL30040512 0.98 CYP1A2 (0.64) CYP1A2CYP2C19POLBRAD52KDM4E
SCHEMBL27097158 0.86 MAOA (0.57) CYP1A2CYP2C19POLBRAD52KDM4E
SCHEMBL18028057 0.82 POLB (0.58) POLBRAD52KMT2ACNR2HTR7
SCHEMBL148312 0.81 MAPT (0.75) CYP1A2CYP2C19POLBKDM4EMAPT
SCHEMBL29540464 0.81 MAPT (0.75) CYP1A2CYP2C19POLBKDM4EMAPT
SCHEMBL27097157 0.80 MAOA (0.59) CYP1A2CYP2C19POLBKDM4EMAPT
SCHEMBL13305152 0.79 SIGMAR1 (0.68) CYP1A2CYP2C19TSHRMEN1KMT2A
SCHEMBL13305182 0.79 TMEM97 (0.64) CNR2HTR7TMEM97SIGMAR1
SCHEMBL18010390 0.78 HTR7 (0.62) CNR2HTR7TMEM97SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed