Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MMP14 | P50281 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112231 | 0.95 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL112230 | 0.95 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL29358253 | 0.95 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL1627083 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL25419671 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL7717321 | 0.87 | POLB (0.58) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL1087160 | 0.86 | MAPT (0.52) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL14994403 | 0.86 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL14994401 | 0.86 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL30887106 | 0.86 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9687057-B2 | Dye composition using a specific non-ionic hydrotropic compound in a medium rich in fatty substances, methods and device | L'OREAL (FR) | 2017-06-27 | — | — | US | disclosed |
| US-9687057-B2 | Dye composition using a specific non-ionic hydrotropic compound in a medium rich in fatty substances, methods and device | L'OREAL (FR) | 2017-06-27 | — | — | US | disclosed |
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-20120204357-A1 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF | L'OREAL (FR) | 2012-08-16 | — | — | US | disclosed |
| WO-2012084820-A2 | COMPOSITION COMPRISING A NATURAL DYE AND/OR A CATIONIC AND/OR NONIONIC DIRECT DYE, AND/OR A DYE PRECURSOR, AN INSOLUBLE SILICATE AND A MONO- OR POLYGLYCOSIDE | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084818-A2 | HAIR DYEING PROCESS USING AN INSOLUBLE SILICATE, AN AROMATIC COMPOUND AND A HYDROXYLATED ALIPHATIC SOLVENT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-2359804-A2 | Composition including an oxidation dye and a derivative of phosphonium or ammonium hydroxide, dyeing of keratin fibres and device | L'Oréal (FR) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011027076-A2 | DYEING METHOD CONSISTING IN APPLYING A METALLIC SALT AND A COMPOSITION CONTAINING A HYDROPHOBIC DYE AND A SPECIFIC COMPOUND | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2011027077-A2 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING | L'OREAL (FR) | 2011-03-10 | — | — | WO | disclosed |
| WO-2010097558-A2 | COMPOSITION CONTAINING A NATURAL OR SYNTHETIC DYE AND AN ALIPHATIC MONOHYDROXYLATED ALCOHOL AND KERATIN FIBRE DYEING METHOD USING SAME | L'OREAL (FR) | 2010-09-02 | — | — | WO | disclosed |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2009-11-19 | — | — | US | disclosed |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'OREAL S.A. (FR) | 2009-11-19 | — | — | US | disclosed |
| EP-2095809-A1 | Composition comprising a hydrophobic colorant and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'Oréal (FR) | 2009-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120204357-A1 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A PARTICULAR ORGANIC AND/OR MINERAL ALKALINE AGENT, A PARTICULAR COMPOUND (I) AND A PARTICULAR ORGANIC COMPOUND (II), AND DYEING USE THEREOF | KRT18, DSG1, DSC1 | KMT2A 1902/4885MEN1 1074/4885MAPT 331/4885 |
| US-20090282624-A1 | Composition comprising a hydrophobic dye and an alkylene carbonate or a lactone and dyeing of keratinous fibres | KRT18, H1-0, H1-5 | KMT2A 2300/4885MEN1 2019/4885MAPT 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.