SCHEMBL29358253

SCHEMBL29358253

Cc1cc(N(CCO)CCO)ccc1N=Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.55
MEN1 O00255 9/20 0.55
MAPT P10636 8/20 0.55
NPC1 O15118 6/20 0.55
RAB9A P51151 6/20 0.55
POLB P06746 5/20 0.55
TDP1 Q9NUW8 4/20 0.55
MAPK1 P28482 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
LMNA P02545 2/20 0.55
MMP14 P50281 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
ALDH1A1 P00352 6/20 0.52
GAA P10253 2/20 0.52
NPSR1 Q6W5P4 2/20 0.48
HTT P42858 2/20 0.48
TSHR P16473 1/20 0.42
HSP90AA1 P07900 2/20 0.40
RECQL P46063 1/20 0.40
TNNI3 P19429 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112230 1.00 KMT2A (0.55) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL112231 1.00 KMT2A (0.55) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL10067503 0.95 KMT2A (0.50) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL25419671 0.92 KMT2A (0.47) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL1627083 0.92 KMT2A (0.47) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL7717321 0.91 POLB (0.58) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL1087160 0.91 MAPT (0.52) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL14994403 0.90 KMT2A (0.46) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL30887106 0.90 KMT2A (0.46) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL14994401 0.90 KMT2A (0.46) KMT2AMEN1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705394-A2 DISPERSE DYES FOR DYEING POLYESTER FIBRES University of Leeds (GB) 2026-03-11 EP claimed
EP-4452210-B1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KAO CORP (JP) 2026-01-14 EP claimed
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KAO CORPORATION (JP) 2025-08-12 US claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
WO-2025036900-A1 HAIR DYEING COMPOSITION KAO CORPORATION (JP) 2025-02-20 WO claimed
US-20250041181-A1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KAO CORPORATION (JP) 2025-02-06 US claimed
WO-2024228036-A2 DYE COMPOUNDS AND METHODS OF USING UNIVERSITY OF LEEDS (GB) 2024-11-07 WO claimed
US-12130267-B2 Analyzing method for azo compound SHIMADZU CORPORATION (JP) 2024-10-29 US claimed
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-24 US claimed
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2023-12-28 US claimed
CN-117222397-A Granular hair dyeing composition 威娜德国有限责任公司 2023-12-12 CN claimed
CN-117054534-A High-flux detection method for fat-soluble synthetic dye in food 广州市食品检验所(广州市酒类检测中心) 2023-11-14 CN claimed
EP-4247323-A2 GRANULATED HAIR DYE COMPOSITION Wella Germany GmbH (DE) 2023-09-27 EP claimed
US-20230225952-A1 ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2023-07-20 US claimed
WO-2023017035-A1 HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS WELLA GERMANY GMBH (DE) 2023-02-16 WO claimed
WO-2022106628-A2 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2022-05-27 WO claimed
EP-3989920-A1 ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF Living Proof, Inc. (US) 2022-05-04 EP claimed
CN-109632988-B Method for detecting content of disperse dye 广州广电计量检测股份有限公司 2022-02-01 CN claimed
US-20220026404-A1 ANALYZING METHOD FOR AZO COMPOUND SHIMADZU CORPORATION (JP) 2022-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents TYR, OGG1, UNG KMT2A 995/4885MEN1 4441/4885MAPT 1644/4885
US-12383480-B2 Dyeing method for keratin fibers comprising a direct azo-dye and an organic alkalizing agent, and kit-of-parts thereof KRT18, PRKCH, PRKCE KMT2A 124/4885MEN1 2560/4885MAPT 2075/4885
US-20230414484-A1 GRANULATED HAIR DYE COMPOSITION SHH, CUTA, DSG1 KMT2A 3273/4885MEN1 4068/4885MAPT 654/4885
US-20250041181-A1 DYEING METHOD FOR KERATIN FIBERS COMPRISING A DIRECT AZO-DYE AND AN ORGANIC ALKALIZING AGENT, AND KIT-OF-PARTS THEREOF KRT18, PRKCH, PRKCE KMT2A 124/4885MEN1 2560/4885MAPT 2075/4885
US-20230225952-A1 ADDITIVES FOR COLORING AGENTS AND METHODS OF USE THEREOF COXFA4L2, TYR, OAT KMT2A 1779/4885MEN1 3502/4885MAPT 1993/4885
US-12364660-B2 Granulated hair dye composition SHH, CUTA, DSG1 KMT2A 3273/4885MEN1 4068/4885MAPT 654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.