Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CES1 | P23141 | 3/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL9736543 | 0.95 | LMNA (0.76) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL8377803 | 0.95 | LMNA (0.76) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL9509478 | 0.91 | ALDH1A1 (0.70) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL27075815 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL2029354 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL3489404 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL6858789 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL28162070 | 0.90 | ALDH1A1 (0.84) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL28486716 | 0.88 | ALDH1A1 (0.73) | LMNAALDH1A1CES1CES2TSHR | |
| Nitrobenzene SCHEMBL28309740 | 0.88 | ALDH1A1 (0.73) | LMNAALDH1A1CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106572658-B | Molecule and relative intermediate, composition and method with certain disinsection efficiencies | 美国陶氏益农公司 | 2019-11-08 | — | — | CN | disclosed |
| EP-2269725-B1 | MICROPUMP DEVICE | SEKISUI CHEMICAL CO LTD (JP) | 2019-10-30 | — | — | EP | disclosed |
| CN-110072857-A | 1, 3-disubstituted cyclobutanone or azetidine derivatives as hematopoietic prostaglandin D synthase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110025574-A | A kind of reduction response type amphipathic stem polymer prodrug and its preparation method and application | 烟台药物研究所 | 2019-07-19 | — | — | CN | disclosed |
| CN-106660988-B | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 勃林格殷格翰国际有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-108926718-A | A kind of amphiphilic polymer prodrug and its preparation method and application of reduction response release raw medicine | 烟台药物研究所 | 2018-12-04 | — | — | CN | disclosed |
| CN-105209443-B | Indoleamine 2, 3-dioxygenase (IDO) inhibitors | 百时美施贵宝公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-108368046-A | Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists | 百时美施贵宝公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108349936-A | It is used to treat N- [2- (1- benzyl piepridine -4- bases) ethyl] -4- (pyrazine -2- bases)-piperazine -1- carboxamides derivatives and related compound of neurological disorder as muscarinic receptor 4 (M4) antagonist | 纽罗克里生物科学有限公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-107573295-A | Molecule and intermediate, composition and its correlation technique with certain agricultural chemicals effectiveness | 美国陶氏益农公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-105209450-B | Molecules and intermediates having pesticidal utility, compositions and methods relating thereto | 美国陶氏益农公司 | 2017-10-20 | — | — | CN | disclosed |
| CN-107253933-A | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 勃林格殷格翰国际有限公司 | 2017-10-17 | — | — | CN | disclosed |
| CN-107105657-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-104817541-B | A kind of synthetic method of antineoplastic | 苏州东南药业股份有限公司 | 2017-06-16 | — | — | CN | disclosed |
| CN-106660988-A | Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity | 勃林格殷格翰国际有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106572658-A | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | 美国陶氏益农公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-103826452-B | Pesticidal compositions and processes related thereto | 陶氏益农公司 | 2017-02-01 | — | — | CN | disclosed |
| US-8353679-B2 | Micropump device | SEKISUI CHEMICAL CO., LTD. (JP) | 2013-01-15 | — | — | US | disclosed |
| US-20110129392-A1 | MICROPUMP DEVICE | SEKISUI CHEMICAL CO., LTD. (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2269725-A1 | MICROPUMP DEVICE | Sekisui Chemical Co., Ltd. (JP) | 2011-01-05 | — | — | EP | disclosed |