Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29396554 | 0.96 | ALDH1A1 (0.64) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL5007718 | 0.96 | ALDH1A1 (0.64) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL10703149 | 0.91 | ALDH1A1 (0.55) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL14950589 | 0.91 | ALDH1A1 (0.49) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL15316784 | 0.90 | ALDH1A1 (0.51) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL14951317 | 0.90 | ALDH1A1 (0.48) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL5007745 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL30365979 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL29363109 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TSHRS100A4RXFP1HPGD | |
| SCHEMBL11955368 | 0.85 | TDP1 (0.55) | ALDH1A1S100A4RXFP1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2515842-B1 | DYEING COMPOSITION COMPRISING A POLYCONDENSATE OF ETHYLENE OXIDE AND PROPYLENE OXIDE | OREAL (FR) | 2020-04-29 | — | — | EP | disclosed |
| US-9687057-B2 | Dye composition using a specific non-ionic hydrotropic compound in a medium rich in fatty substances, methods and device | L'OREAL (FR) | 2017-06-27 | — | — | US | disclosed |
| US-9687057-B2 | Dye composition using a specific non-ionic hydrotropic compound in a medium rich in fatty substances, methods and device | L'OREAL (FR) | 2017-06-27 | — | — | US | disclosed |
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9578944-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-28 | — | — | US | disclosed |
| US-9565915-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9565916-B2 | Compositions and methods for altering the appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| US-9566221-B2 | Methods for altering the color and appearance of hair | L'OREAL (FR) | 2017-02-14 | — | — | US | disclosed |
| EP-2095809-A1 | Composition comprising a hydrophobic colorant and an alkylene carbonate or a lactone and dyeing of keratinous fibres | L'Oréal (FR) | 2009-09-02 | — | — | EP | disclosed |
| EP-2074986-A1 | Process for treating hair fibres using polysiloxane/polyurea | L'Oréal (FR) | 2009-07-01 | — | — | EP | disclosed |
| US-20080184496-A1 | Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
| US-20080184496-A1 | Composition comprising a compound X and A compound Y, at least one of which is a silicone, and a hydrophobic direct dye | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
| EP-1935403-A2 | Composition containing a compound x and a compound y, at least one of which is silicone, and a hydrophobic direct dye | L'Oréal (FR) | 2008-06-25 | — | — | EP | disclosed |
| EP-1935404-A1 | Composition for dyeing keratinous fibres comprising a polysiloxane-polyurea block copolymer | L'Oréal (FR) | 2008-06-25 | — | — | EP | disclosed |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'OREAL S.A. (FR) | 2008-06-05 | — | — | US | disclosed |
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | L'OREAL S.A. (FR) | 2008-06-05 | — | — | US | disclosed |
| US-7364596-B2 | Dye compositions comprising at least one hydrophobic direct dye and at least one acid | L'OREAL S.A. (FR) | 2008-04-29 | — | — | US | disclosed |
| US-7364596-B2 | Dye compositions comprising at least one hydrophobic direct dye and at least one acid | L'OREAL S.A. (FR) | 2008-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080127429-A1 | Coloring composition of keratinous fibers comprising at least one polysiloxane/polyurea block copolymer | KRT18, PUF60, VIM | ALDH1A1 2435/4885TSHR 4756/4885S100A4 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.