Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007718 | 0.92 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL29396554 | 0.92 | ALDH1A1 (0.64) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL10067790 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL10703149 | 0.87 | ALDH1A1 (0.55) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL12269537 | 0.87 | S100A4 (0.46) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL5007745 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL30365979 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL29363109 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDRXFP1MEN1 | |
| SCHEMBL10057893 | 0.83 | S100A4 (0.51) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL14950589 | 0.82 | ALDH1A1 (0.49) | ALDH1A1TSHRHPGDRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8579993-B2 | Use of dyestuffs for dyeing keratin fibers and compositions comprising the dyestuffs | KAO GERMANY GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20130269121-A1 | USE OF DYESTUFFS FOR DYEING KERATIN FIBERS AND COMPOSITIONS COMPRISING THE DYESTUFFS | KAO GERMANY GMBH (DE) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130269121-A1 | USE OF DYESTUFFS FOR DYEING KERATIN FIBERS AND COMPOSITIONS COMPRISING THE DYESTUFFS | KRT18, DOHH, CHCHD3 | ALDH1A1 639/4885TSHR 3740/4885HPGD 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.