Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846871 | 0.99 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL18071858 | 0.99 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL5011561 | 0.99 | TDP1 (0.54) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL80507 | 0.95 | TDP1 (0.61) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL19728591 | 0.88 | TDP1 (0.47) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL19728600 | 0.86 | TDP1 (0.43) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL13038973 | 0.85 | ALDH1A1 (0.46) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL10067790 | 0.85 | ALDH1A1 (0.58) | TDP1L3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL14365729 | 0.83 | KDM4E (0.51) | TDP1L3MBTL1KDM4ENPSR1S100A4 | |
| SCHEMBL14452202 | 0.83 | S100A4 (0.43) | TDP1L3MBTL1KDM4EMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120192887-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | The Marbury Law Group, PLLC | 2012-08-02 | — | — | US | disclosed |
| US-20120192887-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | The Marbury Law Group, PLLC | 2012-08-02 | — | — | US | disclosed |
| US-20090155198-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | L'OREAL, S.A. (FR) | 2009-06-18 | — | — | US | disclosed |
| US-20090155198-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | L'OREAL, S.A. (FR) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155198-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | PUF60, POLR1C, PCBP1 | TDP1 1794/4885L3MBTL1 3860/4885KDM4E 2130/4885 |
| US-20120192887-A1 | PROCESS FOR TREATING HAIR FIBERS USING POLYSILOXANE/POLYUREA | PUF60, POLR1C, PCBP1 | TDP1 1794/4885L3MBTL1 3860/4885KDM4E 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.