Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77605 | 0.81 | ADORA3 (0.47) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL13026590 | 0.80 | SMN1; SMN2 (0.81) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL19116581 | 0.80 | SMN1; SMN2 (0.81) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL10068186 | 0.80 | XIAP (0.49) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL10079027 | 0.78 | NPC1 (0.58) | SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL19116850 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL10183380 | 0.78 | KDM4E (0.57) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL29177265 | 0.78 | RAB9A (0.49) | SMN1; SMN2RAB9ALMNANPC1MAPT | |
| SCHEMBL10082887 | 0.78 | SMN1; SMN2 (0.77) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A | |
| SCHEMBL20935124 | 0.78 | SMN1; SMN2 (0.77) | SMN1; SMN2ADORA1ADORA3ADORA2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | SMN1; SMN2 4458/4885ADORA1 4324/4885ADORA3 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.