Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77586 | 0.90 | NPC1 (0.49) | ADORA3ADORA1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL821743 | 0.85 | SMN1; SMN2 (0.61) | ADORA3ADORA1ADORA2ASMN1; SMN2NPC1 | |
| SCHEMBL2400372 | 0.82 | CLK4 (0.45) | — | |
| SCHEMBL10068156 | 0.81 | ALDH1A1 (0.60) | ADORA3ADORA1ADORA2ASMN1; SMN2NPC1 | |
| SCHEMBL10068191 | 0.81 | SMN1; SMN2 (0.74) | ADORA3ADORA1ADORA2ASMN1; SMN2NPC1 | |
| SCHEMBL10079027 | 0.79 | NPC1 (0.58) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10068142 | 0.79 | EPHX1 (0.49) | SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10183380 | 0.79 | KDM4E (0.57) | ADORA3ADORA1ADORA2ASMN1; SMN2RAB9A | |
| SCHEMBL29177265 | 0.79 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10068157 | 0.78 | HPGD (0.47) | SMN1; SMN2NPC1RAB9AMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | ADORA3 3923/4885ADORA1 4378/4885ADORA2A 4609/4885 |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | ADORA3 3786/4885ADORA1 4324/4885ADORA2A 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.