SCHEMBL10068337

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL679848	0.92	SMN1; SMN2 (0.55)	ACHENPC1RAB9AKMT2AMEN1
	SCHEMBL13463285	0.89	ACHE (0.56)	ACHEMAOBNPC1RAB9AKMT2A
	SCHEMBL12345146	0.88	ACHE (0.54)	ACHEMAOBNPC1RAB9AKMT2A
	SCHEMBL10072185	0.86	ACACB (0.46)	ACHEMAOBKMT2AMEN1SMN1; SMN2
	SCHEMBL24767596	0.85	CYP1A1 (0.48)	MAOBNPC1RAB9AKMT2AMEN1
	SCHEMBL14301863	0.85	MEN1 (0.52)	MAOBNPC1RAB9AKMT2AMEN1
	SCHEMBL13614276	0.85	SMN1; SMN2 (0.48)	ACHERAB9AKMT2AMEN1SMN1; SMN2
	SCHEMBL29083061	0.85	ESR2 (0.59)	NPC1RAB9AKMT2AMEN1CASP3
	SCHEMBL14457620	0.85	TDP1 (0.54)	NPC1RAB9AKMT2AMEN1SMN1; SMN2
	SCHEMBL7822185	0.84	ESR2 (0.55)	NPC1RAB9AKMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.