Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412641 | 0.92 | GRM5 (0.42) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL412062 | 0.82 | MAOA (0.50) | MAOAMAOB | |
| SCHEMBL411601 | 0.81 | MAOA (0.40) | GRM5MAOAMAOB | |
| SCHEMBL411056 | 0.78 | CALML3 (0.47) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL411600 | 0.78 | F10 (0.44) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL412061 | 0.77 | F10 (0.45) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL411159 | 0.77 | TDO2 (0.39) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL469913 | 0.76 | CALML3 (0.44) | MAOAMAOB | |
| SCHEMBL411602 | 0.75 | F10 (0.38) | GRM5MAOAMAOBGRM2 | |
| SCHEMBL10068630 | 0.75 | TDO2 (0.42) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |