Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742469 | 0.81 | ELANE (0.56) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL14189455 | 0.81 | ELANE (0.56) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL10068631 | 0.77 | SIGMAR1 (0.41) | ALDH1A1KMT2AMEN1TSHRMAPK1 | |
| SCHEMBL10038027 | 0.76 | BRD4 (0.32) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6621178 | 0.74 | KMT2A (0.54) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL6623233 | 0.71 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL16775234 | 0.70 | KMT2A (0.70) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL16759895 | 0.70 | KMT2A (0.70) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL6747735 | 0.70 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL7829113 | 0.70 | ALDH1A1 (0.93) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9592497-B2 | Process for the asymmetric hydrogenation of imides | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-03-14 | — | — | US | disclosed |
| US-20120165546-A1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF IMIDES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-28 | — | — | US | disclosed |
| WO-2010145024-A1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF IMIDES | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165546-A1 | PROCESS FOR THE ASYMMETRIC HYDROGENATION OF IMIDES | IDH2, HRH4, HPSE | ALDH1A1 1874/4885KMT2A 540/4885MEN1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.