SCHEMBL1006864

SCHEMBL1006864

CCOc1ccccc1C(=O)OC(=O)OC(=O)c1ccccc1OCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.58
L3MBTL1 Q9Y468 4/20 0.51
GLA P06280 1/20 0.51
MAPT P10636 4/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 1/20 0.51
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
KMT2A Q03164 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
MEN1 O00255 1/20 0.50
KDM4E B2RXH2 3/20 0.49
LMNA P02545 2/20 0.49
HTT P42858 1/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 2/20 0.48
ATM Q13315 1/20 0.48
KCNK3 O14649 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992535 0.93 HCRTR1 (0.62) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL6589832 0.88 HCRTR1 (0.57) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL8587610 0.88 HCRTR1 (0.57) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL18224473 0.88 HCRTR1 (0.57) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL4343858 0.88 ESR1 (0.51) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL1009321 0.86 ADRB2 (0.53) L3MBTL1MAPTALDH1A1KMT2ANPSR1
Bicarbonate SCHEMBL7114860 0.86 ESR1 (0.50) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL6464181 0.85 HCRTR1 (0.62) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL4282830 0.85 HCRTR1 (0.62) HCRTR1L3MBTL1GLAMAPTALDH1A1
SCHEMBL1006617 0.85 LMNA (0.59) L3MBTL1MAPTALDH1A1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 534 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1723191-B1 LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME SABIC GLOBAL TECHNOLOGIES BV (NL) 2015-07-22 EP claimed
US-8865833-B2 Polycarbonate composition comprising nanomaterials SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-10-21 US claimed
US-7666977-B2 Poly(carbonate-co-urea) copolymers and melt transesterification method of preparing these copolymers SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-23 US claimed
EP-1577333-B1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP (NL) 2008-12-03 EP claimed
WO-2008136841-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-11-13 WO claimed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
EP-1504048-B1 METHOD OF PREPARING POLYESTERCARBONATES GEN ELECTRIC (US) 2007-11-21 EP claimed
US-7211641-B2 high heat resistance, outstanding dimensional stability and excellent solvent resistance GENERAL ELECTRIC COMPANY (US) 2007-05-01 US claimed
EP-1723191-A1 LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2006-11-22 EP claimed
WO-2005085319-A1 LIQUID CRYSTAL POLYCARBONATES AND METHODS OF PREPARING SAME GENERAL ELECTRIC COMPANY (US) 2005-09-15 WO claimed
US-20050192424-A1 Liquid crystal polycarbonates and methods of preparing same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2005-09-01 US claimed
EP-1508141-A1 METHOD OF ENHANCING PIT REPLICATION IN OPTICAL DISKS General Electric Company, (a New York Corporation) (US) 2005-02-23 EP claimed
EP-1504048-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-02-09 EP claimed
US-6734277-B2 POLYCARBONATE COMPOSITIONS INCORPORATING LONG CHAIN ALKYLPHENOL ENDGROUPS GENERAL ELECTRIC COMPANY 2004-05-11 US claimed
WO-2003096330-A1 METHOD OF ENHANCING PIT REPLICATION IN OPTICAL DISKS GENERAL ELECTRIC COMPANY (US) 2003-11-20 WO claimed
US-20030212241-A1 Method of enhancing pit replication in optical disks GENERAL ELECTRIC COMPANY 2003-11-13 US claimed
WO-2003087190-A1 METHOD OF PREPARING POLYESTERCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-10-23 WO claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US claimed
EP-4621010-A1 IMPACT PERFORMANCE MODIFIED MELT POLYCARBONATE SABIC Global Technologies B.V. (NL) 2025-09-24 EP disclosed
US-6504002-B1 Melt strength GENERAL ELECTRIC COMPANY 2003-01-07 US disclosed