SCHEMBL4282830

SCHEMBL4282830

CCOc1ccccc1C(=O)OO

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.62
L3MBTL1 Q9Y468 4/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 4/20 0.54
GAA P10253 1/20 0.54
MAPK1 P28482 1/20 0.54
ALDH1A1 P00352 2/20 0.54
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TSHR P16473 1/20 0.52
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 2/20 0.51
HTT P42858 1/20 0.51
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28992535 0.89 HCRTR1 (0.62) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL6464181 0.89 HCRTR1 (0.62) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL536025 0.87 TSHR (0.71) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL30553984 0.87 HCRTR1 (0.65) HCRTR1L3MBTL1MAPTGAAMAPK1
SCHEMBL1989129 0.87 HCRTR1 (0.65) HCRTR1L3MBTL1MAPTGAAMAPK1
SCHEMBL24074018 0.85 HCRTR1 (0.58) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL1006864 0.85 HCRTR1 (0.58) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL29196402 0.85 LMNA (0.59) L3MBTL1MAPTALDH1A1KMT2AMEN1
SCHEMBL7945834 0.85 HCRTR1 (0.58) HCRTR1L3MBTL1GLAMAPTGAA
SCHEMBL7057320 0.85 HCRTR1 (0.58) HCRTR1L3MBTL1GLAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111194206-A Composition containing benzoic acid derivatives or furoic acid derivatives and use of the derivatives for emulsion and foam stability 西姆莱斯股份公司 2020-05-22 CN claimed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1287043-A4 A METHOD FOR PRODUCING ETHYLENE HOMO- AND CO-POLYMER SAMSUNG GENERAL CHEMICALS CO (KR) 2004-08-25 EP claimed
EP-1287043-A1 A METHOD FOR PRODUCING ETHYLENE HOMO- AND CO-POLYMER Samsung General Chemicals Co., Ltd. (KR) 2003-03-05 EP claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
WO-2001092345-A1 A METHOD FOR PRODUCING ETHYLENE HOMO- AND CO-POLYMER SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2001-12-06 WO claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICALC., LTD. (JP) 2026-04-23 US disclosed
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 US disclosed
US-20220265613-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-08-25 US disclosed
US-20200078340-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-03-12 US disclosed
US-20190070151-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2019-03-07 US disclosed
US-RE46792-E1 Oxazole compound and pharmaceutical composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2018-04-17 US disclosed
WO-2007058338-A9 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMA CO LTD (JP) 2007-11-01 WO disclosed
WO-2007058338-A2 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-05-24 WO disclosed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US disclosed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP disclosed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP disclosed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A HCRTR1 1318/4885L3MBTL1 4602/4885GLA 1627/4885
US-20260108497-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE7B, PDE4B, PDE1B HCRTR1 3861/4885L3MBTL1 4619/4885GLA 2368/4885
US-20200078340-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A HCRTR1 1318/4885L3MBTL1 4602/4885GLA 1627/4885
US-20220265613-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A HCRTR1 1254/4885L3MBTL1 4706/4885GLA 2019/4885
US-20190070151-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION PDE3B, PDE4A, PDE3A HCRTR1 1318/4885L3MBTL1 4602/4885GLA 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.