Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 15/20 | 0.74 |
| ▸ | CA1 | P00915 | 14/20 | 0.74 |
| ▸ | CA12 | O43570 | 8/20 | 0.74 |
| ▸ | CA9 | Q16790 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CA7 | P43166 | 6/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL672750 | 0.85 | CA2 (1.00) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL1626262 | 0.84 | ALDH1A1 (0.56) | CA2CA1CA12CA9CA7 | |
| SCHEMBL15247285 | 0.84 | ALDH1A1 (0.56) | CA2CA1CA12CA9CA7 | |
| SCHEMBL9492114 | 0.83 | ALDH1A1 (0.55) | CA2CA1CA12CA9CA7 | |
| SCHEMBL28499329 | 0.81 | KMT2A (1.00) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL10068897 | 0.80 | CA2 (0.64) | CA2CA1CA12CA9KMT2A | |
| SCHEMBL19445300 | 0.78 | RAB9A (0.60) | KMT2AMEN1 | |
| SCHEMBL9923561 | 0.78 | CA1 (1.00) | CA2CA1CA12CA9CA7 | |
| SCHEMBL6382778 | 0.77 | TSHR (0.62) | KMT2AMEN1 | |
| SCHEMBL9280164 | 0.77 | PTPN7 (1.00) | CA2CA1CA12CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021963-A1 | NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH | METASIGNAL THERAPEUTICS INC. (CA) | 2012-02-23 | — | — | WO | disclosed |