Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CTSL | P07711 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004729 | 0.85 | CTSS (0.36) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL2028799 | 0.85 | CTSS (0.36) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL1568409 | 0.79 | CTSS (0.38) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL7998383 | 0.78 | CTSD (0.37) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL8002296 | 0.78 | CTSS (0.37) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL19401001 | 0.73 | CTSS (0.35) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL5321090 | 0.73 | CTSS (0.36) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL5321089 | 0.73 | CTSS (0.36) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL10069059 | 0.73 | CTSS (0.52) | CTSSCTSLCTSBCTSDCTSK | |
| SCHEMBL227128 | 0.72 | CTSD (0.39) | CTSSCTSLCTSBCTSDCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |