Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069240 | 0.93 | ALDH1A1 (0.38) | CYP2A6ALDH1A1NOS3NOS1GRM2 | |
| SCHEMBL10068677 | 0.92 | CYP2A6 (0.47) | CYP2A6ALDH1A1IDH1NOS3NOS1 | |
| SCHEMBL19505954 | 0.91 | CYP2A6 (0.37) | CYP2A6ALDH1A1NOS3NOS1GRM2 | |
| SCHEMBL19885517 | 0.91 | ALDH1A1 (0.30) | CYP2A6ALDH1A1 | |
| SCHEMBL10038679 | 0.91 | ALDH1A1 (0.30) | CYP2A6ALDH1A1 | |
| SCHEMBL10068689 | 0.87 | CRHBP (0.37) | CYP2A6ALDH1A1NOS3NOS1GFER | |
| SCHEMBL10118867 | 0.86 | ALDH1A1 (0.42) | CYP2A6ALDH1A1NOS3NOS1GFER | |
| SCHEMBL10068678 | 0.85 | CYP2A6 (0.35) | CYP2A6ALDH1A1IDH1GFERHCRTR2 | |
| SCHEMBL10069123 | 0.85 | CYP2A6 (0.51) | CYP2A6ALDH1A1IDH1NOS3NOS1 | |
| SCHEMBL10068832 | 0.84 | ALDH1A1 (0.33) | CYP2A6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9923146-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2018-03-20 | — | — | US | disclosed |
| US-20170309822-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20160181527-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2016-06-23 | — | — | US | disclosed |
| US-9331285-B2 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20120013244-A1 | ORGANIC LUMINESCENT MEDIUM | IDEMITSU KOSAN CO., LTD. | 2012-01-19 | — | — | US | disclosed |
| US-20110297923-A1 | Aromatic amine derivative and organic electroluminescent element using same | IDEMITSU KOSAN CO., LTD. | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120013244-A1 | ORGANIC LUMINESCENT MEDIUM | ANXA1, ANXA11, GLB1 | CYP2A6 1167/4885ALDH1A1 61/4885IDH1 539/4885 |
| US-20170309822-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME | H1-4, H1-2, H1-0 | CYP2A6 3351/4885ALDH1A1 672/4885IDH1 2706/4885 |
| US-20110297923-A1 | Aromatic amine derivative and organic electroluminescent element using same | H1-4, H1-2, H1-0 | CYP2A6 3351/4885ALDH1A1 672/4885IDH1 2706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.