SCHEMBL10069245

SCHEMBL10069245

Cc1cccc(N(c2cccc(C#N)c2)c2cc(C(C)C)c3ccc4c(N(c5cccc(C)c5)c5cccc(C#N)c5)cc(C(C)C)c5ccc2c3c54)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLQ O75417 1/20 0.34
IDO1 P14902 2/20 0.34
GFER P55789 1/20 0.32
S1PR1 P21453 1/20 0.31
KCNN4 O15554 1/20 0.31
KCNA5 P22460 1/20 0.31
AR P10275 1/20 0.31
PER2 O15055 1/20 0.31
CRY1 Q16526 1/20 0.31
CRY2 Q49AN0 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.30
GLA P06280 1/20 0.30
ENPP2 Q13822 1/20 0.30
TBXA2R P21731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10069231 0.92 GFER (0.38) POLQIDO1GFERS1PR1AR
SCHEMBL10038758 0.91 POLQ (0.35) POLQ
SCHEMBL10068681 0.90 KCNA5 (0.39) S1PR1KCNN4KCNA5PER2CRY1
SCHEMBL10068679 0.90 GFER (0.36) POLQIDO1GFER
SCHEMBL10353951 0.89 ACHE (0.32) POLQ
SCHEMBL21870115 0.85 THRB (0.34) POLQGLA
SCHEMBL10038759 0.84 POLQ (0.37) POLQIDO1GFER
SCHEMBL10038696 0.83 POLQ (0.36) POLQGFER
SCHEMBL18789860 0.82 MARK3 (0.33) S1PR1
SCHEMBL10038698 0.82 KCNN4 (0.34) KCNN4KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9923146-B2 Aromatic amine derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-20170309822-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-10-26 US disclosed
US-20160181527-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20120013244-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120013244-A1 ORGANIC LUMINESCENT MEDIUM ANXA1, ANXA11, GLB1 POLQ 3106/4885IDO1 1081/4885GFER 1638/4885
US-20170309822-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME H1-4, H1-2, H1-0 POLQ 2109/4885IDO1 1197/4885GFER 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.