SCHEMBL10068679

SCHEMBL10068679

Cc1cccc(N(c2ccc(C#N)cc2)c2cc(C(C)C)c3ccc4c(N(c5ccccc5)c5ccc(C#N)cc5)cc(C(C)C)c5ccc2c3c54)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.36
POLQ O75417 1/20 0.35
IDO1 P14902 2/20 0.33
KCNH2 Q12809 1/20 0.31
SCN10A Q9Y5Y9 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31
RORC P51449 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10069231 0.98 GFER (0.38) GFERPOLQIDO1KCNH2SCN10A
SCHEMBL10038696 0.92 POLQ (0.36) GFERPOLQ
SCHEMBL17933033 0.92 CRHBP (0.35) PTGDR2RORCCRHBPCRHR2
SCHEMBL10068685 0.92 CRHBP (0.35) PTGDR2RORCCRHBPCRHR2
SCHEMBL10038759 0.90 POLQ (0.37) GFERPOLQIDO1
SCHEMBL10069245 0.90 POLQ (0.34) GFERPOLQIDO1
SCHEMBL21870115 0.89 THRB (0.34) POLQ
SCHEMBL10068832 0.87 ALDH1A1 (0.33)
SCHEMBL10068681 0.87 KCNA5 (0.39) RORC
SCHEMBL10069131 0.87 ALDH1A1 (0.42) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120013244-A1 ORGANIC LUMINESCENT MEDIUM IDEMITSU KOSAN CO., LTD. 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120013244-A1 ORGANIC LUMINESCENT MEDIUM ANXA1, ANXA11, GLB1 GFER 1638/4885POLQ 3106/4885IDO1 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.