Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412569 | 0.96 | SHMT2 (0.37) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL13259586 | 0.96 | SHMT2 (0.37) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL10018465 | 0.94 | SMN1; SMN2 (0.39) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL26319852 | 0.94 | SMN1; SMN2 (0.39) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL10018461 | 0.94 | SMN1; SMN2 (0.39) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL13259595 | 0.92 | SHMT2 (0.34) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL10018459 | 0.91 | SHMT2 (0.35) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL22893526 | 0.91 | TDP1 (0.38) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL12132256 | 0.91 | TDP1 (0.40) | SHMT2TDP1SMN1; SMN2HTTPKM | |
| SCHEMBL10018462 | 0.90 | SHMT2 (0.34) | SHMT2TDP1SMN1; SMN2HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8192905-B2 | Electrophotographic photoconductor, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2012-06-05 | — | — | US | disclosed |
| US-20070248901-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2007-10-25 | — | — | US | disclosed |