SCHEMBL26319852

SCHEMBL26319852

CCCCCCCC(C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(N1C(=O)c2ccc4c5c(ccc(c25)C1=O)C(=O)N(C(C)CCCCC)C4=O)C3=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
SHMT2 P34897 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 1/20 0.35
CES1 P23141 2/20 0.33
TERT O14746 2/20 0.33
CDC25A P30304 1/20 0.33
TP53 P04637 1/20 0.33
HSP90AA1 P07900 1/20 0.33
CYP3A4 P08684 1/20 0.33
G6PD P11413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018465 1.00 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL10018461 1.00 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL412569 0.98 SHMT2 (0.37) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL13259586 0.98 SHMT2 (0.37) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL10069249 0.94 SHMT2 (0.35) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL10018459 0.94 SHMT2 (0.35) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL22893526 0.94 TDP1 (0.38) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL12132256 0.94 TDP1 (0.40) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL10018462 0.93 SHMT2 (0.34) SMN1; SMN2HSD17B10PKMHTTALDH1A1
SCHEMBL13285164 0.93 SHMT2 (0.37) SMN1; SMN2HSD17B10PKMHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed