SCHEMBL412569

SCHEMBL412569

CCCCCC(C)N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(N1C(=O)c2ccc4c5c(ccc(c25)C1=O)C(=O)N(C(C)CCCCC)C4=O)C3=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHMT2 P34897 1/20 0.37
TDP1 Q9NUW8 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
HTT P42858 3/20 0.36
PKM P14618 1/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP2C19 P33261 1/20 0.35
TERT O14746 3/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
PIN1 Q13526 1/20 0.33
PIN4 Q9Y237 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13259586 1.00 SHMT2 (0.37) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL26319852 0.98 SMN1; SMN2 (0.39) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL10018465 0.98 SMN1; SMN2 (0.39) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL10018461 0.98 SMN1; SMN2 (0.39) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL10018459 0.96 SHMT2 (0.35) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL10069249 0.96 SHMT2 (0.35) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL22893526 0.95 TDP1 (0.38) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL12132256 0.95 TDP1 (0.40) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL10018462 0.94 SHMT2 (0.34) SHMT2TDP1SMN1; SMN2HTTPKM
SCHEMBL13285164 0.94 SHMT2 (0.37) SHMT2TDP1SMN1; SMN2HTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9958796-B2 Electrophotographic photoreceptor, image forming method, and image forming apparatus Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-9958796-B2 Electrophotographic photoreceptor, image forming method, and image forming apparatus Konica Minolta, Inc. (JP) 2018-05-01 US disclosed
US-20170261870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2017-09-14 US disclosed
US-20170261870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2017-09-14 US disclosed
US-20160252834-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-09-01 US disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9141008-B2 Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound CANON KABUSHIKI KAISHA (JP) 2015-09-22 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20070264047-A1 IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2007-11-15 US disclosed
US-20070248901-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-25 US disclosed
US-20070219375-A1 Novel Compound and Organic Electronic Device Using the Same MITSUI CHEMICALS, INC. (JP) 2007-09-20 US disclosed
US-20070219375-A1 Novel Compound and Organic Electronic Device Using the Same MITSUI CHEMICALS, INC. (JP) 2007-09-20 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059618-A1 Electrophotographic photoconductor, and image forming apparatus, process cartridge and image forming method using the same RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059618-A1 Electrophotographic photoconductor, and image forming apparatus, process cartridge and image forming method using the same RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059039-A1 Electrophotographic image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059039-A1 Electrophotographic image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219375-A1 Novel Compound and Organic Electronic Device Using the Same OR10J3, RPS10, NOX4 SHMT2 1788/4885TDP1 3638/4885SMN1; SMN2 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.