SCHEMBL10069262

SCHEMBL10069262

C=CC(=O)Nc1ccc(/N=N/c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 6/20 0.82
▸ MEN1 O00255 7/20 0.54
▸ KMT2A Q03164 7/20 0.54
▸ LMNA P02545 2/20 0.49
▸ F13A1 P00488 1/20 0.49
▸ TGM1 P22735 1/20 0.49
▸ TGM3 Q08188 1/20 0.49
▸ RAB9A P51151 4/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ MAPT P10636 3/20 0.47
▸ MAPK1 P28482 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ POLB P06746 2/20 0.47
▸ NPSR1 Q6W5P4 2/20 0.47
▸ HTT P42858 1/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ NAMPT P43490 1/20 0.47
▸ MITF O75030 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ MYOC Q99972 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919472 0.91 TGM2 (1.00) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL14690419 0.86 TGM2 (0.63) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL13219021 0.80 KMT2A (0.68) MEN1KMT2ALMNARAB9AALDH1A1
SCHEMBL4342393 0.80 TGM2 (0.70) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL910367 0.80 TGM2 (0.70) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL9538114 0.79 TGM2 (0.51) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL9538116 0.79 TGM2 (0.51) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL3261323 0.79 MEN1 (0.53) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL3261324 0.79 MEN1 (0.53) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL18780313 0.78 TGM2 (0.59) TGM2LMNAF13A1TGM1TGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 — — US disclosed
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS E INK CORPORATION 2018-02-08 — — US disclosed
WO-2016096091-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2016-06-23 — — WO disclosed
US-9115464-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2015-08-25 — — US disclosed
US-8743451-B2 Coloured particles for electrophoretic displays MERCK PATENT GMBH (DE) 2014-06-03 — — US disclosed
US-20120041165-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2012-02-16 — — US disclosed
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-15 — — US disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 — — US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037744-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, GYPA, SELP TGM2 3854/4885MEN1 3915/4885KMT2A 4104/4885
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE TGM2 3794/4885MEN1 3924/4885KMT2A 4291/4885
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, IK, SELP TGM2 4005/4885MEN1 4319/4885KMT2A 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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