SCHEMBL3919472

SCHEMBL3919472

C=CC(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TGM2 P21980 8/20 1.00
▸ MEN1 O00255 6/20 0.65
▸ KMT2A Q03164 6/20 0.65
▸ LMNA P02545 2/20 0.58
▸ F13A1 P00488 1/20 0.58
▸ TGM1 P22735 1/20 0.58
▸ TGM3 Q08188 1/20 0.58
▸ RAB9A P51151 3/20 0.54
▸ NPC1 O15118 3/20 0.54
▸ MAPT P10636 3/20 0.54
▸ MAPK1 P28482 3/20 0.54
▸ NAMPT P43490 1/20 0.54
▸ MITF O75030 1/20 0.54
▸ POLB P06746 1/20 0.54
▸ GAA P10253 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ MYOC Q99972 1/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10069262 0.91 TGM2 (0.82) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL10012491 0.84 TGM2 (0.70) TGM2MEN1KMT2ALMNAF13A1
SCHEMBL30448387 0.84 TGM2 (0.72) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL10414259 0.83 TGM2 (0.71) TGM2MEN1KMT2ALMNANPC1
SCHEMBL439369 0.82 TGM2 (0.79) TGM2LMNAF13A1TGM1TGM3
SCHEMBL5149342 0.80 KMT2A (0.69) TGM2MEN1KMT2ANPC1MAPT
SCHEMBL6631700 0.79 KMT2A (0.71) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL4588400 0.79 KMT2A (0.71) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL9351738 0.79 ALDH1A1 (0.72) TGM2MEN1KMT2ALMNARAB9A
SCHEMBL31596017 0.79 TGM2 (0.66) TGM2MEN1KMT2ALMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-12-25 — — US claimed
US-20250298042-A1 ENGINEERED PARTICLES AS RED BLOOD CELL MIMICS AND COMPOSITIONS CONTAINING SAME FOR HEMATOLOGY SLINGSHOT BIOSCIENCES, INC. (US) 2025-09-25 — — US claimed
EP-4608872-A2 SIZE-TUNABLE SYNTHETIC PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME FOR IMMUNE CELL ACTIVATION Slingshot Biosciences, Inc. (US) 2025-09-03 — — EP claimed
US-12379387-B2 Engineered particles as red blood cell mimics and compositions containing same for hematology SLINGSHOT BIOSCIENCES, INC. (US) 2025-08-05 — — US claimed
EP-3256850-B1 HYDROGEL PARTICLES WITH TUNABLE OPTICAL PROPERTIES AND METHODS FOR USING THE SAME SLINGSHOT BIOSCIENCES INC (US) 2025-07-09 — — EP claimed
US-12352679-B2 Synthetic human cell mimic particle for cytometric or coulter device SLINGSHOT BIOSCIENCES, INC. (US) 2025-07-08 — — US claimed
EP-4577823-A2 COMPOSITIONS AND METHODS FOR SINGLE WELL MULTIPLEXED CALIBRATION AND COMPENSATION Slingshot Biosciences, Inc. (US) 2025-07-02 — — EP claimed
US-20250189428-A1 COMPOSITIONS AND METHODS FOR SINGLE WELL MULTIPLEXED CALIBRATION AND COMPENSATION SLINGSHOT BIOSCIENCES, INC. (US) 2025-06-12 — — US claimed
US-12312595-B2 Hydrogel particles as feeder cells and as synthetic antigen presenting cells SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-27 — — US claimed
US-20250164373-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE SLINGSHOT BIOSCIENCES, INC. (US) 2025-05-22 — — US claimed
US-6673886-B2 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2004-01-06 — — US claimed
US-6657030-B2 High refractive index and hydrophilic monomers, a crosslinker, an initiator and water BAUSCH & LOMB INCORPORATED 2003-12-02 — — US claimed
US-6657029-B2 High refractive index monomer, greater amount of a hydrophilic monomer, crosslinker, and initiator; give water content; intraocular lenses BAUSCH & LOMB INCORPORATED 2003-12-02 — — US claimed
US-6555711-B1 Reacting an N-allylimino nitrobenzene compound with a diamino-dinucleophile to form an alpha-amino-N- allylamidino-nitrobenzene compound; chemical intermediate for a pyrazolo(1,5-b)(1,2,4)triazole color photographic coupler EASTMAN KODAK COMPANY 2003-04-29 — — US claimed
US-20020049290-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-25 — — US claimed
US-20020042483-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-04-11 — — US claimed
US-20020042484-A1 High refractive index hydrogel compositions for ophthalmic implants BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2002-04-11 — — US claimed
US-20020037984-A1 High refractive index hydrogel compositions for ophthalmic implants VANDERBILT DAVID P (US) 2002-03-28 — — US claimed
US-6329485-B1 FOR INTRAOCULAR LENSES BAUSCH & LOMB INCORPORATED 2001-12-11 — — US claimed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389633-A1 SYNTHETIC HUMAN CELL MIMIC PARTICLE FOR CYTOMETRIC OR COULTER DEVICE CD4, ICOS, CD69 TGM2 1495/4885MEN1 3203/4885KMT2A 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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