Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468002 | 0.92 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL10069323 | 0.91 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL12284075 | 0.90 | ALDH1A1 (0.41) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL10069338 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL2555031 | 0.85 | CA12 (0.43) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL2559609 | 0.82 | KDM4E (0.47) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL24750118 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL30768370 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL2556818 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL24819230 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019428-A1 | BENZOHYDROL DERIVATIVES, A PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-02-16 | — | — | WO | disclosed |