Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.43 |
| ▸ | CALML3 | P27482 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463740 | 0.93 | CALML3 (0.51) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL469913 | 0.83 | CALML3 (0.44) | MAOACALML3MAOBTDO2CYP2C19 | |
| SCHEMBL463725 | 0.82 | MAOA (0.50) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL463249 | 0.82 | TDO2 (0.41) | MAOACALML3MAOBTDO2 | |
| SCHEMBL463272 | 0.81 | F10 (0.53) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL463557 | 0.81 | MAOA (0.49) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL463591 | 0.81 | MAOA (0.49) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL12964788 | 0.80 | CALML3 (0.48) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL4168134 | 0.80 | MAOA (0.58) | MAOACALML3MAOBCYP3A4CYP2C19 | |
| SCHEMBL4168138 | 0.80 | MAOA (0.58) | MAOACALML3MAOBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033952-A1 | 3 - PHENYL- 2 -OXO- 1, 3 -OXAZOLIDINES FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | WO | disclosed |