Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9551055 | 1.00 | POLB (0.54) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL26092410 | 1.00 | POLB (0.54) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL5005472 | 0.91 | KMT2A (0.62) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL268927 | 0.86 | RXFP1 (0.61) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL268926 | 0.86 | RXFP1 (0.61) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL13219021 | 0.85 | KMT2A (0.68) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL9193033 | 0.83 | TGM2 (0.54) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL9193038 | 0.83 | TGM2 (0.54) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL4126180 | 0.80 | MAPT (0.70) | POLBKMT2AMEN1NPC1MAPT | |
| SCHEMBL10491540 | 0.80 | MAPT (0.70) | POLBKMT2AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435566-B2 | Particles for electrophoretic displays | MERCK PATENT GMBH (DE) | 2019-10-08 | — | — | US | disclosed |
| US-20180037744-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | E INK CORPORATION | 2018-02-08 | — | — | US | disclosed |
| WO-2016096091-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-9115464-B2 | Particles for electrophoretic displays | MERCK PATENT GMBH (DE) | 2015-08-25 | — | — | US | disclosed |
| US-8743451-B2 | Coloured particles for electrophoretic displays | MERCK PATENT GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-20120041165-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-02-16 | — | — | US | disclosed |
| US-20110306742-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-12-15 | — | — | US | disclosed |
| US-20110297888-A1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-12-08 | — | — | US | disclosed |
| WO-2010089057-A2 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010089060-A2 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2010-08-12 | — | — | WO | disclosed |
| WO-2010089059-A1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037744-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | RAB5IF, GYPA, SELP | POLB 1024/4885KMT2A 4104/4885MEN1 3915/4885 |
| US-10435566-B2 | Particles for electrophoretic displays | RAB5IF, SELP, SELE | POLB 1448/4885KMT2A 4291/4885MEN1 3924/4885 |
| US-20110306742-A1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | RAB5IF, IK, SELP | POLB 1248/4885KMT2A 4136/4885MEN1 4319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.