SCHEMBL268927

SCHEMBL268927

C=C(C)C(=O)Nc1ccc(N=Nc2ccc(NC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.61
MAPT P10636 10/20 0.58
RAB9A P51151 6/20 0.58
SMN1; SMN2 Q16637 6/20 0.58
NPC1 O15118 5/20 0.58
LMNA P02545 3/20 0.58
HPGD P15428 2/20 0.58
NFKB1 P19838 1/20 0.58
NFKB2 Q00653 1/20 0.58
RELA Q04206 1/20 0.58
TDP1 Q9NUW8 5/20 0.50
L3MBTL1 Q9Y468 3/20 0.45
POLB P06746 2/20 0.45
THRB P10828 1/20 0.45
RECQL P46063 1/20 0.45
BLM P54132 1/20 0.45
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
ALDH1A1 P00352 5/20 0.45
KDM4E B2RXH2 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL268926 1.00 RXFP1 (0.61) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL10491540 0.93 MAPT (0.70) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL4126180 0.93 MAPT (0.70) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL31238515 0.92 MAPT (0.53) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL14613097 0.89 L3MBTL1 (0.58) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL13609822 0.89 NPC1 (0.55) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL439393 0.88 RXFP1 (0.74) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL9551055 0.86 POLB (0.54) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL10070045 0.86 POLB (0.54) RXFP1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL26092410 0.86 POLB (0.54) RXFP1MAPTRAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119133264-A Airport low reflection photovoltaic module 山东欧圣达新能源有限公司 2024-12-13 CN claimed
US-9890351-B2 Encapsulates THE PROCTER & GAMBLE COMPANY (US) 2018-02-13 US claimed
US-8772355-B2 Stealth polymeric particles for delivery of bioactive or diagnostic agents HOWARD UNIVERSITY (US) 2014-07-08 US claimed
EP-2643372-A2 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS Howard University (US) 2013-10-02 EP claimed
WO-2012071452-A2 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS HOWARD UNIVERSITY (US) 2012-05-31 WO claimed
US-20120129798-A1 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-05-24 US claimed
US-5415864-A Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1995-05-16 US claimed
CN-120519150-B Up-conversion fluorescent probe, isoniazid detection method and portable isoniazid detection sensor 中国科学院合肥物质科学研究院 2025-11-18 CN disclosed
CN-120519150-A Up-conversion fluorescent probe, isoniazid detection method and portable isoniazid detection sensor 中国科学院合肥物质科学研究院 2025-08-22 CN disclosed
CN-119133264-A Airport low reflection photovoltaic module 山东欧圣达新能源有限公司 2024-12-13 CN disclosed
CN-116075573-A Sulfonated polymers 沙特阿拉伯石油公司 2023-05-05 CN disclosed
CN-115551443-A Base integrated restoration block for cutting and manufacturing method thereof 株式会社哈斯 2022-12-30 CN disclosed
US-11366357-B2 Liquid crystal display device, production method for liquid crystal display device, and retardation layer-forming monomer SHARP KABUSHIKI KAISHA (JP) 2022-06-21 US disclosed
US-5603953-A HYDROPHILIC MATERIAL SURROUNDED BY MICROPOROUS SUPPORTING WALL HAVING HYDROPHOBIC LIQUID ENTRAINED IN PORES, WITH VARIABLE WATER PERMEABILITY, FOR CONTROLLED DRUG DELIVERY PFIZER INC. (US) 1997-02-18 US disclosed
EP-0670717-A1 SUPPORTED LIQUID MEMBRANE DELIVERY DEVICES PFIZER INC. (US) 1995-09-13 EP disclosed
US-5415864-A Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1995-05-16 US disclosed
WO-1994012159-A1 SUPPORTED LIQUID MEMBRANE DELIVERY DEVICES PFIZER INC. (US) 1994-06-09 WO disclosed
EP-0544671-A4 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING PH-DEPENDENT SWELLING 1993-09-15 EP disclosed
EP-0544671-A1 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1993-06-09 EP disclosed
WO-1991016057-A1 COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING UNIVERSITY OF UTAH (US) 1991-10-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120129798-A1 STEALTH POLYMERIC PARTICLES FOR DELIVERY OF BIOACTIVE OR DIAGNOSTIC AGENTS SSTR5, SSTR3, SSTR1 RXFP1 1090/4885MAPT 2486/4885RAB9A 3487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.