Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070736 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL112618 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| Alcohol SCHEMBL5316638 | 0.95 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL22833075 | 0.93 | MEN1 (0.48) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL5370214 | 0.87 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL16357610 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL3973634 | 0.84 | MEN1 (0.32) | MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL13296191 | 0.83 | TSHR (0.44) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL12844291 | 0.83 | MEN1 (0.42) | ALDH1A1MEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL1517434 | 0.82 | MEN1 (0.36) | MEN1KMT2ACYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165300-A1 | DIASTEREOMERS OF 2-METHYLENE-19-NOR-22-METHYL-1ALPHA,25-DIHYDROXYVITAMIN D3 | CYP24A1, CYP2R1, CYP27B1 | ALDH1A1 759/4885MEN1 379/4885KMT2A 2983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.